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Forty-six states currently allow children to be exempt from vaccinations due to religious concerns, including 17 states that also allow exemptions for “personal reasons,” according to a Pew Research Center analysis.One state, Minnesota, allows parents to not vaccinate their children based on a broader “personal” exemption that does not explicitly mention religion.When it comes to state-mandated vaccines, you can lead a horse to water, but you can’t make that horse (or in this case, Americans) take the vaccine.At least that’s the case with Gardasil, a vaccine that protects against nine strains of human papillomavirus, or HPV.The newest version of Gardasil, which got FDA approval in December 2014, protects against nine strains of HPV and 90% of all cancers associated with the virus.The first version only protected against four strains, including the two responsible for 70% of cervical cancer.

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Below are a variety of events associated with the establishment of vaccination mandates and the role of government agencies in monitoring vaccine production and use.

Vaccines have made huge inroads over recent decades – dramatically shrinking the numbers of people affected by potentially deadly diseases such as measles, whooping cough, influenza and polio. medical experts spoke with CBS News for World Immunization Week (April 24 – 30) and raised concern about the number of Americans who still aren’t vaccinating their children or getting their own shots, which continues to fuel preventable disease outbreaks. Colleges have been particularly hard hit by the mumps.

But an additional 1.5 million deaths could be prevented across the globe if more people were immunized, says the World Health Organization. In 2015-2016, the two largest outbreaks happened in Iowa and Illinois, each involving several hundred university students.

The New York City Board of Health told the Health Department to devise a plan to ensure the purity and potency of diphtheria antitoxins sold in the city. Congress passed "An act to regulate the sale of viruses, serums, toxins, and analogous products," later referred to as the Biologics Control Act (even though "biologics" appears nowhere in the law). Public Health Service to oversee manufacture of biological drugs.

At this point, most of the antitoxin came from two suppliers in Germany. This was the first modern federal legislation to control the quality of drugs. The Hygienic Laboratory eventually became the National Institutes of Health.

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A Royal Canadian Mounted Police officer informs a migrant couple of the location of a legal border station, shortly before they illegally crossing from Champlain, N. (AP Photo/Charles Krupa) " data-medium-file="https://shawglobalnews.files.wordpress.com/2017/08/nyck111-87_2017_172147_high1.jpg? quality=70&strip=all&w=300" data-large-file="https://shawglobalnews.files.wordpress.com/2017/08/nyck111-87_2017_172147_high1.jpg? quality=70&strip=all&w=650" /Canada’s first prime minister, Sir John A. THE CANADIAN PRESS/National Archive of Canada " data-medium-file="https://shawglobalnews.files.wordpress.com/2013/10/cpt500137542_high-e1421006619118.jpg?